CORIOLIN, A NEW BASIDIOMYCETES ANTIBIOTIC

Coriolin, a new Basidiomycetes antibiotic.

Collybial, a new antibiotic sesquiterpenoid from Collybia confluens (Basidiomycetes).

A new antibiotic was isolated from fermentations of an american strain of Collybia confluens. Its structure was elucidated by spectroscopic methods as 2,10,10-trimethal-4-oxo-tricyclo[7.2.0.0(2.5)]undec-6- en-carbaldehyde (with the relative stereo chemistry 1S, 2R, 5R, 9R) (1). The inhibitor, which was named collybial, is structurally related to koraiol, a sesquiterpenoid isolated from Pinus ko...

Antibiotic Substances from Basidiomycetes Ix

Antibiotic Substances from Basidiomycetes: III. Coprinus Similis and Lentinus Degener.

* Journal Paper No. J-1578 of the Iowa Agricultural Experiment Station. Project No. 746. 1 Ajl, S. J., White, A. G. C., and Werkman, C. H., J. Bact., 54, 23 (1947). 2 Kalnitsky, G., Utter, M. F., and Werkman, C. H., Ibid., 49, 595-602 (1947). 3 Ochoa, S., J. Biol. Chem., 155, 87-100 (1944). 4 Quastel, J. H., and Wooldridge, W. R., Biochem. J., 22, 689-702 (1922). 5 Klotz, I. M., and Tietze, F.,...

ANTIBIOTICS FROM BASIDIOMYCETES XXXIL* STROBILURIN E: A NEW CYTOSTATIC AND ANTIFUNGAL (£)-£-METHOXYACRYLATE ANTIBIOTIC FROM CREPIDO TUS FUL VO TOMENTOSUS PECKá"

The strobilurins, oudemansins and related synthetic mimics constitute a new class of respiration inhibitors which inhibit the electron transfer in the bcx complex. These compounds, both natural and synthetic, contain an (£)-/?-methoxyacrylate (MOA) moiety which is responsible for the antifungal and respiration inhibiting properties2). Strobilurin E was detected and isolated in the course of a s...